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Editorials

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Glia: Non-neural Players in Orofacial Pain

  • Barry J. Sessle

DOI: 10.11607/jofph.21.3.01 Vol.21,Issue 3,September 2007 pp.169-170

Published: 30 September 2007

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Barry J. Sessle. Glia: Non-neural Players in Orofacial Pain. Journal of Oral & Facial Pain and Headache. 2007. 21(3);169-170.

References

1. Salter MW. Cellular neuroplasticity mechanisms mediating pain persistence. J Orofac Pain 2004;18:318–324.

2. Watkins LR, Maier SF. Glia and pain: Past, present, and future. In: Merskey H, Loeser D, Dubner R (eds). The Paths of Pain 1975–2005. Seattle: IASP Press, 2005: 165–175.

3. Yeo JF, Liu HP, Leong SK. Sustained microglial immunoreactivity in the caudal spinal trigeminal nucleus after formalin injection. J Dent Res 2001;80:1524–1529.

4. Piao ZG, Cho IH, Park CK, et al. Activation of glia and microglia p38MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury. Pain 2006;121:219–231.

5. Yang CS, Jung CY, Ju JS, Lee MK, Ahn DK. Intracisternal administration of mitogen-activated protein kinase inhibitors reduced IL-1beta-induced mirror-image mechanical allodynia in the orofacial area of rats. Neurosci Lett 2005;387:32–37.

6. Guo W, Wang H, Watanabe M, et al. Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. J Neurosci 2007;27:6006–6018.

7. Xie YF, Zhang S, Chiang CY, Hu JW, Dostrovsky JO, Sessle BJ. Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn). Brain Behav Immun 2007;21:634–641.

8. Chiang CY, Wang J, Xie YF, et al. Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn. J Neurosci (in press).

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